A Novel Experience in Treatment of Liver Hydatidosis in Pediatrics: A Clinical Trial Study

نویسندگان

  • Aghigh Ziaee-mehr Surgical Oncology Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Ali Alamdaran Surgical Oncology Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Ali Azadmand Surgical Oncology Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Amir mohammad Dalili Medical Student, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Elham Bazrafshan Surgical Oncology Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Elmira Zohorian Surgical Oncology Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Farideh Jamali-Behnam Surgical Oncology Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Khalil Alizadeh Surgical Oncology Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Mahdi Parvizi- Mashhadi Surgical Oncology Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Marjan Joodi Surgical Oncology Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Mehdi Fathi Surgical Oncology Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Morteza Peyvandi Surgical Oncology Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Reza Nazarzadeh Surgical Oncology Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
چکیده مقاله:

  Background Hydatidosis is a conventional health public problem in most parts of the world. Safe treatment of patients with hydatidosis has been a topic of debate for a long time. Surgical treatment always was associated with high morbidity and mortality. Medical treatment is also controversial. In this study, alternative procedure named Percutaneous, Aspiration and hypertonic Saline Instillation (PAHSI) was applied to treat patients with hydatidosis. Materials and Methods In this single-blind clinical trial, thirty-eight patients, ranging in age between 6 months and 16 years, with 81 hepatic hydatid cysts underwent PAHSI treatment. The consecutive steps including sonographic guidance, aspiration of cyst content and injection of 15% saline hypertonic were carried out in this method. Patients with multiple cysts also were treated by this procedure. Results Participants were 18 boys (47.3%) and 20 girls (52.6%) with mean age of 8.08+ 3.92 years. Almost half of the patients had single cyst (52.63%). During 2- year follow- up, no recurrences were observed; therefore, re-hospitalization and possible complications reduced considerably. Furthermore, this method was applicable to cure multiple cysts. Conclusion In PAHSI strategy, it seems that the complications of surgery (laparotomy and anesthesia) decreased since no complications observed after procedure, and cosmetic results in future are much better due to avoidance of incision.

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عنوان ژورنال

دوره 5  شماره 10

صفحات  5945- 5952

تاریخ انتشار 2017-10-01

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